3d 1 Avogadro 2 Molecular editor and visualiser for chemistry and materials science. Agriculture 2 farmOS Farm record keeping and planning: log plantings, harvests, inputs, observations and equipment maintenance against mapped fields and beds, track livestock and inventory, and keep the audit trail that organic and food-safety certification asks for. Audio 3 openDAW Browser-based digital audio workstation with a Rust/WASM engine. CAM 4 MosaicSlicer In-browser 3D print slicer: CuraEngine compiled to WebAssembly slices STL/3MF models into G-code for FDM printers, with a MicroPython WASM runtime for custom post-processing and device scripts. Chemistry 5 Ketcher Chemical structure editor: draw molecules and reactions, check valences, generate SMILES/InChI, and edit macromolecules (peptides, RNA/DNA, CHEM) — with the Indigo cheminformatics engine compiled to WebAssembly so every calculation runs locally. 6 Mol* Molecular visualisation for structural biology and chemistry: renders proteins, nucleic acids, ligands, density maps and trajectories in the browser, reading mmCIF, PDB, SDF, MOL2, XYZ and MDTraj formats. The viewer behind RCSB PDB and PDBe. Data 7 OpenRefine Clean and reconcile messy data: load spreadsheets, CSV, JSON or XML, cluster near-duplicate values, split and transform columns with GREL, reconcile entities against Wikidata, and keep a full undo history you can replay on the next batch. 8 QGIS Full desktop GIS: analyse spatial data, build maps, run geoprocessing, all open source. Education 9 Stellarium Planetarium — render the sky from any point on Earth at any time, with deep-sky catalogs and telescope control. Electronics 10 LibrePCB Electronics design automation: draw schematics, assign parts from a shared component library, lay out and route printed circuit boards, check design rules, and export Gerber, Excellon and 3D STEP for manufacturing. Energy 11 VeraGrid Power systems analysis and planning: build transmission and distribution grids, run power flow, optimal power flow, short circuit, contingency and time-series studies, and model wind, solar and storage for research or professional network planning. Geospatial 12 WebODM Drone mapping from your own imagery: upload aerial photos and get orthophotos, digital surface and terrain models, contours, point clouds and textured 3D meshes, then measure areas, volumes and elevation profiles on the result. Healthcare 13 Weasis DICOM viewer for medical imaging — multiplanar reconstruction, measurements, export. Knowledge 14 Datashare Search a document collection the way an investigative desk does: point it at a folder of PDFs, emails, spreadsheets and scans, and it extracts the text — running OCR over the images — indexes every document, pulls out the people, organisations and places named in them, and lets you run saved batch searches across the lot. Built by the ICIJ for the Panama Papers, and everything stays on this machine. 15 Kiwix The whole of Wikipedia offline, and much else besides: open ZIM archives of Wikipedia, Wiktionary, Project Gutenberg, Stack Exchange, TED and medical libraries, then read and full-text search them with no connection at all.